Description

(1S,2S,3'R,4'bS,7'S,8'aS,9'S,10'S)-3',10'-Bis(acetyloxy)-4'b,5',6',7',8',8'a,9',10'-octahydro-9'-hydroxy-2,4'b,7'-trimethyl-8'-methylenespiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is a complex, high-purity diterpenoid derivative with a unique spirocyclic structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold in synthetic organic chemistry for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for exploring new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex natural product analogs and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new molecules with targeted biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed in advanced synthetic methodologies due to its intricate stereochemistry and functional groups, useful for constructing complex molecular architectures.
• Biochemical Research: Potential use as a probe or ligand in studying enzyme interactions or biological pathways, given its diterpenoid backbone.

Basic Information

Product Name	(1S,2S,3'R,4'bS,7'S,8'aS,9'S,10'S)-3',10'-Bis(acetyloxy)-4'b,5',6',7',8',8'a,9',10'-octahydro-9'-hydroxy-2,4'b,7'-trimethyl-8'-methylenespiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione
CAS No.	56246-56-1
Molecular Formula	C26H34O7
Molecular Weight	458.55 g/mol
Synonyms	3',10'-Diacetoxy-9'-hydroxy-2,4'b,7'-trimethyl-8'-methylenespiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione; Spiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione derivative; Diterpenoid spirocyclic diacetate; 56246-56-1; (1S,2S)-3',10'-Bis(acetyloxy)-9'-hydroxy-2,4'b,7'-trimethyl-8'-methylenespiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and development activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.