Description

(2S,1S,3'R,4'bS,7'R,8'aR,9'S,10'S)-3',7',9'-Triacetoxy-4'b,5',6',7',8',8'a,9',10'-octahydro-10'-hydroxy-2,4'b,8',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is a complex, high-purity steroidal derivative with a unique spirocyclic structure. This compound is valued as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized steroids and hormone analogs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and hormone-based therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its biological activity and potential interactions with steroid receptors in academic and institutional research.
• Process Chemistry: Employed in the development and scale-up of complex synthetic routes within fine chemical production.

Basic Information

Product Name	(2S,1S,3'R,4'bS,7'R,8'aR,9'S,10'S)-3',7',9'-Triacetoxy-4'b,5',6',7',8',8'a,9',10'-octahydro-10'-hydroxy-2,4'b,8',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione
CAS No.	56197-48-9
Molecular Formula	C29H38O9
Molecular Weight	530.61 g/mol
Synonyms	3',7',9'-Triacetoxy-10'-hydroxy-2,4'b,8',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione; Spiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione derivative; 56197-48-9; 3β,7β,9α-Triacetoxy-11β-hydroxy-4,4,14α-trimethyl-5β-gonane-20-spirocyclopropane-12-one (alternative steroidal naming); Steroidal Spirocyclopropane Derivative; Advanced Steroid Intermediate
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical-grade intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.