Description

(3R,3'aR,5S,7'aα)-1',4,5,5',6',8',8'aβ,9'aβ-Octahydro-5-(3-furyl)-4'α,9'bα-dihydroxy-6'β-methylspiro[furan-3(2H),7'(4'H)-oxireno[2,3]naphtho[1,8a-c]furan]-1',2(7'aH)-dione is a complex, high-purity spirocyclic furan derivative with a defined stereochemistry, identified by CAS number 54927-89-8. This compound is valued for its intricate molecular architecture, which serves as a critical advanced intermediate in the synthesis of novel pharmaceutical agents and fine chemicals. It is primarily sought by research institutions and pharmaceutical development teams working on new drug candidates and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and anti-infective therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D labs to study complex cyclization reactions, stereoselective synthesis, and the construction of polycyclic frameworks.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new bioactive molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical purity and complex furan-based structures.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in laboratories characterizing similar complex molecules.

Basic Information

Item	Details
Product Name	(3R,3'aR,5S,7'aα)-1',4,5,5',6',8',8'aβ,9'aβ-Octahydro-5-(3-furyl)-4'α,9'bα-dihydroxy-6'β-methylspiro[furan-3(2H),7'(4'H)-oxireno[2,3]naphtho[1,8a-c]furan]-1',2(7'aH)-dione
CAS No.	54927-89-8
Molecular Formula	C22H24O8
Molecular Weight	416.42 g/mol
Synonyms	Spiraeoside derivative (complex furan); Oxirenonaphthofurandione; CAS 54927-89-8; (3R,3'aR,5S,7'aα)-Spirofuranoxirenofurandione; 5-(3-Furyl)octahydrospiro[furan-3,7'-oxireno[2,3]naphtho[1,8a-c]furan]dione; Advanced Spirocyclic Furan Intermediate; Light-sensitive Furan Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support compliance with cGMP standards for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.