Description

(5'R,3S,2R,4''aR)-4,5,3',4',3'',4'',4a'',5'',6'',7'',8'',8a''-Dodecahydro-5''α-(hydroxymethyl)-2''α,5'',8''aβ-trimethyldispiro[furan-3(2H),2'(5'H)-furan-5',1''(2''H)-naphthalene]-2,6''β-diol is a complex, high-purity spirocyclic diterpenoid compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block and key intermediate for developing novel therapeutic agents. This compound is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex natural products and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly for complex natural product derivatives.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective synthesis due to its multiple defined chiral centers.
• Natural Product Synthesis: A key compound for the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Biochemical Research: Potential use as a standard or probe in studying enzymatic pathways or biological interactions related to diterpenoid metabolism.
• Fine Chemical Production: Used in the manufacture of high-value, specialty chemicals for research and development purposes.

Basic Information

Product Name	(5'R,3S,2R,4''aR)-4,5,3',4',3'',4'',4a'',5'',6'',7'',8'',8a''-Dodecahydro-5''α-(hydroxymethyl)-2''α,5'',8''aβ-trimethyldispiro[furan-3(2H),2'(5'H)-furan-5',1''(2''H)-naphthalene]-2,6''β-diol
CAS No.	53823-01-1
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	Dispiro[furan-3(2H),2'(5'H)-furan-5',1''(2''H)-naphthalene]-2,6''-diol, dodecahydro-5''-(hydroxymethyl)-2'',5'',8''a-trimethyl-, [2R-(2α,3β,5'R*,4''aR*)]-; (2R,3S,5'R,4''aR)-Dodecahydro-5''-(hydroxymethyl)-2'',5'',8''a-trimethyldispiro[furan-3(2H),2'(5'H)-furan-5',1''(2''H)-naphthalene]-2,6''-diol; Aconitane-1,7,8,14-tetrol, 20-ethyl-4-methyl-8-(1-methylethyl)-, (1α,7β,8α,14α,16β)-; Lappaconitine related compound; Norditerpenoid alkaloid intermediate; Spiroditerpenoid diol
EINECS	Contact for details

Quality Control

Our (5'R,3S,2R,4''aR)-4,5,3',4',3'',4'',4a'',5'',6'',7'',8'',8a''-Dodecahydro-5''α-(hydroxymethyl)-2''α,5'',8''aβ-trimethyldispiro[furan-3(2H),2'(5'H)-furan-5',1''(2''H)-naphthalene]-2,6''β-diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can supply material compliant with research-grade and custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.