Description

2-[2-Amino-4,7-dihydro-3-(methoxycarbonyl)thieno[2,3-c]pyridin-6(5H)-yl]-3-chloro-5-(trifluoromethyl)pyridine, 2-Amino-6-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(methoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new agrochemicals, where its heterocyclic core may contribute to novel modes of action for pesticides or herbicides.
• Organic Synthesis Building Block: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) and create diverse chemical libraries for high-throughput screening.
• Contract Research & Development (CRO/CMO): Supplied to contract research organizations and contract manufacturing organizations for client-specific custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Item	Details
Product Name	2-[2-Amino-4,7-dihydro-3-(methoxycarbonyl)thieno[2,3-c]pyridin-6(5H)-yl]-3-chloro-5-(trifluoromethyl)pyridine, 2-Amino-6-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(methoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine
CAS No.	321430-29-9
Molecular Formula	C16H15ClF3N3O2S
Molecular Weight	405.82 g/mol
Synonyms	2-Amino-6-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(methoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine; 2-[2-Amino-4,7-dihydro-3-(methoxycarbonyl)thieno[2,3-c]pyridin-6(5H)-yl]-3-chloro-5-(trifluoromethyl)pyridine; CAS 321430-29-9; Thieno[2,3-c]pyridine derivative; 3-Chloro-5-(trifluoromethyl)pyridine-thienopyridine conjugate
EINECS	Contact for details

Quality Control

Our 2-[2-Amino-4,7-dihydro-3-(methoxycarbonyl)thieno[2,3-c]pyridin-6(5H)-yl]-3-chloro-5-(trifluoromethyl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.