Description

5-Carboxy-2-[7-[5-carboxy-1,3-dihydro-3,3-diMethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-diMethyl-1-(4-sulfobutyl)-3H-indoliuM MonosodiuM Salt is a high-purity, water-soluble cyanine dye derivative, valued for its strong near-infrared (NIR) absorption and fluorescence properties. This compound is critical for advanced diagnostic and research applications where precise optical signaling is required. It is primarily utilized by manufacturers and research institutions in the biotechnology, medical diagnostics, and analytical chemistry sectors.

Application

• Fluorescent Labeling Agent: Used as a covalent tag for biomolecules (proteins, antibodies, nucleic acids) in fluorescence-based assays and imaging.
• NIR Imaging Probes: A key component in the synthesis of contrast agents for non-invasive in vivo imaging and bio-distribution studies.
• Diagnostic Kits: Incorporated into lateral flow assays, ELISA, and other point-of-care diagnostic devices for sensitive detection.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer in the development of novel cancer treatments.
• Material Science: Employed in the development of organic semiconductors, solar cells, and optical sensors due to its photophysical characteristics.
• Flow Cytometry: Serves as a fluorescent dye for cell sorting and analysis in research and clinical flow cytometers.

Basic Information

Product Name	5-Carboxy-2-[7-[5-carboxy-1,3-dihydro-3,3-diMethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-diMethyl-1-(4-sulfobutyl)-3H-indoliuM MonosodiuM Salt
CAS No.	308127-43-7
Molecular Formula	C37H45N2O10S2Na
Molecular Weight	764.88 g/mol
Synonyms	IR-783 carboxylic acid; Sulfo-Cy7.5 carboxylic acid; NIR Cyanine dye acid; 1-(4-Sulfobutyl)-3,3-dimethyl-2-[7-(1,3,3-trimethyl-5-sulfonatobutyl-1,3-dihydro-2H-indol-2-ylidene)-1,3,5-heptatrienyl]-1H-indolium-5-carboxylate sodium salt; Cy7.5-COOH; Heptamethine cyanine dye derivative; 5-Carboxyindole cyanine dye sodium salt
EINECS	Contact for details

Quality Control

Our production of 5-Carboxy-2-[7-[5-carboxy-1,3-dihydro-3,3-diMethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-diMethyl-1-(4-sulfobutyl)-3H-indoliuM MonosodiuM Salt adheres to stringent quality management protocols. Every batch is characterized by advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to ensure identity, purity, and batch-to-batch consistency suitable for research and diagnostic applications. Comprehensive Certificates of Analysis (COA) detailing purity, absorbance/fluorescence profiles, and impurity limits are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled temperature between 2°C and 8°C (refrigerated). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference standard
Purity (HPLC, Area %)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Absorption Max (λmax)	783 nm ± 5 nm
Emission Max (λem)	~810 nm
Extinction Coefficient (ε)	≥ 200,000 M-1cm-1
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.