Description

(1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-1a,4a,5,6,7,7a,8,10,11,11a-Decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethylspiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-4(1H)-one is a high-purity, complex sesquiterpene lactone derivative with a unique spirocyclic and epoxide structure. This compound is valued for its potential as a key chiral intermediate or reference standard in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical manufacturing.
• Agrochemical Research: Acts as a precursor or model compound in the development of new pesticides or herbicides with specific biological activity.
• Academic & Institutional Research: Employed in universities and research institutes for studying complex organic reactions, natural product synthesis, and structure-activity relationships (SAR).
• Process Chemistry Development: Utilized for scaling up synthetic routes, optimizing catalytic processes, and developing cost-effective manufacturing pathways for complex molecules.

Basic Information

Product Name	(1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-1a,4a,5,6,7,7a,8,10,11,11a-Decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethylspiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-4(1H)-one
CAS No.	28649-60-7
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	4(1H)-Spiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-one, 1a,4a,5,6,7,7a,8,10,11,11a-decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethyl-, (1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-; Parthenolide derivative; Spirocyclic sesquiterpene lactone; Epoxy sesquiterpenoid; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1aR,2E,4aR,6S,7S,7aR,8S,9R,11aS)-1a,4a,5,6,7,7a,8,10,11,11a-Decahydro-4a,7,8-trihydroxy-1,1,3,6-tetramethylspiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-4(1H)-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.