Description

(3S,8R,9S,12S)-3,12-Bis(1,1-diMethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylMethyl)-6-[[4-(2-pyridinyl)phenyl]Methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-DiMethyl Ester is a complex, high-purity synthetic organic compound characterized by its specific stereochemistry and multifunctional molecular architecture. This compound matters as a critical advanced pharmaceutical intermediate or research-grade chemical building block for the development of novel therapeutic agents, particularly in targeted drug discovery. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and academic research sectors working on complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Drug Discovery & Medicinal Chemistry: Used in research laboratories for structure-activity relationship (SAR) studies and the development of new chemical entities with specific biological activities.
• Peptidomimetic Research: Its structure suggests utility in the design and synthesis of peptidomimetics—molecules that mimic the structure and function of peptides—for therapeutic applications.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for investigating biological pathways and protein interactions.
• Process Development & Scale-up: Supports process chemistry efforts to optimize synthetic routes from milligram to kilogram scale for preclinical and clinical material supply.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Item	Details
Product Name	(3S,8R,9S,12S)-3,12-Bis(1,1-diMethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylMethyl)-6-[[4-(2-pyridinyl)phenyl]Methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-DiMethyl Ester
CAS No.	1292296-09-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,14-Dimethyl (3S,8R,9S,12S)-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-9-benzyl-6-[4-(pyridin-2-yl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate; A complex peptidomimetic derivative; Advanced pharmaceutical intermediate 1292296-09-3; Custom synthetic building block CAS 1292296-09-3; (3S,8R,9S,12S)-3,12-Di-tert-butyl-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-{[4-(pyridin-2-yl)phenyl]methyl}-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our (3S,8R,9S,12S)-3,12-Bis(1,1-diMethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylMethyl)-6-[[4-(2-pyridinyl)phenyl]Methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-DiMethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (by HPLC), chiral purity, and related substances are provided and available upon request. Our quality commitment aligns with the standards expected for pharmaceutical R&D and GMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (typically 15-25°C) or as specified on the label or COA. For long-term storage, consider storing under an inert atmosphere at a lower temperature (e.g., -20°C) to maximize stability, as the compound may be sensitive to oxidation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.