Description

IMidodicarbonic acid, 2-[1-[(3aS,4R,6aR)-3a,6a-dihydro-2,2-diMethyl-6-[(triphenylMethoxy)Methyl]-4H-cyclopenta-1,3-dioxol-4-yl]-1H-iMidazo[4,5-c]pyridin-4-yl]-, 1,3-bis(1,1-diMethylethyl) ester is a sophisticated, high-purity chemical intermediate designed for advanced synthetic applications. This compound is critical for research and development in pharmaceutical chemistry, where it serves as a key building block for complex molecular architectures. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and complex heterocyclic compounds.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, enabling the exploration of new chemical space and structure-activity relationships (SAR).
• Process Chemistry Development: Serves as a protected intermediate in the scale-up and optimization of synthetic routes for target molecules under Good Manufacturing Practice (GMP) conditions.
• Nucleoside & Nucleotide Chemistry: Integral to the synthesis of modified nucleosides and nucleotides, which are essential for antiviral and anticancer therapeutics.
• Bioconjugation & Probe Development: Can be utilized in the creation of labeled probes and bioconjugates for diagnostic and biochemical research applications.
• Academic & Contract Research: A valuable reagent for universities and contract research organizations (CROs) engaged in cutting-edge organic synthesis and chemical biology projects.

Basic Information

Item	Details
Product Name	IMidodicarbonic acid, 2-[1-[(3aS,4R,6aR)-3a,6a-dihydro-2,2-diMethyl-6-[(triphenylMethoxy)Methyl]-4H-cyclopenta-1,3-dioxol-4-yl]-1H-iMidazo[4,5-c]pyridin-4-yl]-, 1,3-bis(1,1-diMethylethyl) ester
CAS No.	1207561-02-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,3-Di-tert-butyl 2-[1-[(3aS,4R,6aR)-3a,6a-dihydro-2,2-dimethyl-6-[(triphenylmethoxy)methyl]-4H-cyclopenta-1,3-dioxol-4-yl]-1H-imidazo[4,5-c]pyridin-4-yl]imidodicarbonate; 2-[1-[(3aS,4R,6aR)-3a,6a-Dihydro-2,2-dimethyl-6-[(triphenylmethoxy)methyl]-4H-cyclopenta-1,3-dioxol-4-yl]-1H-imidazo[4,5-c]pyridin-4-yl]imidodicarbonic acid 1,3-bis(1,1-dimethylethyl) ester; Di-tert-butyl N-[1-[(3aS,4R,6aR)-3a,6a-dihydro-2,2-dimethyl-6-[(triphenylmethoxy)methyl]-4H-cyclopenta-1,3-dioxol-4-yl]-1H-imidazo[4,5-c]pyridin-4-yl]imidodicarbonate; Protected nucleoside intermediate; TBDMS-protected imidodicarbonate ester.
EINECS	Contact for details

Quality Control

Our IMidodicarbonic acid ester intermediate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical synthesis. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We adhere to relevant quality guidelines suitable for non-GMP and GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.