Description

The mixture of TERT-BUTYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CYCLOHEX-3-ENYLCARBAMATE and tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enylcarbamate is a high-purity, advanced pharmaceutical intermediate containing a pinacol boronate ester functional group. This compound is a critical building block in modern synthetic organic chemistry, enabling the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex carbon-carbon bonds. It is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials and liquid crystals via cross-coupling reactions.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial manufacturing of fine chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry and catalysis studies.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds for biochemical assays and diagnostic tools.

Basic Information

Item	Details
Product Name	The mixture of TERT-BUTYL 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)CYCLOHEX-3-ENYLCARBAMATE and tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-enylcarbamate
CAS No.	1175298-10-8
Molecular Formula	C17H30BNO4 (for each isomer)
Molecular Weight	323.24 g/mol
Synonyms	tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-ylcarbamate (Isomer mixture); 3-((tert-Butoxycarbonyl)amino)cyclohex-3-ene-1-boronic acid pinacol ester; 3-(Boc-amino)cyclohex-3-ene-1-boronic acid pinacol ester; (3-((tert-Butoxycarbonyl)amino)cyclohex-3-en-1-yl)boronic acid pinacol ester; N-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexen-1-amine; CAS 1175298-10-8; Cyclohex-3-ene-1-boronic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- (stereoisomer).
EINECS	Contact for details

Quality Control

Our production of this boronate ester intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), isomeric ratio, and impurity profiles are provided with each shipment. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and prevent hydrolysis of the boronate ester.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Total isomers)
Isomeric Ratio (HPLC)	Specified on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.