Description

Pinacolborane is a highly versatile and reactive organoboron reagent, essential for modern synthetic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing carbon-carbon bonds. This makes it a critical raw material for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the pinacol boronate ester functional group into complex molecules, facilitating crucial coupling steps in API (Active Pharmaceutical Ingredient) development.
• Agrochemical Production: Used in the synthesis of novel herbicides, fungicides, and insecticides by constructing biaryl and heteroaryl structures central to their activity.
• Material Science & OLED Development: Employed in the synthesis of conjugated polymers and organic light-emitting diode (OLED) materials, where precise control over molecular architecture is required.
• Cross-Coupling Reactions: The quintessential reagent for Suzuki-Miyaura cross-couplings with aryl and vinyl halides, offering excellent functional group tolerance and mild reaction conditions.
• Petrochemical Research: Utilized in catalytic studies and the development of novel ligands and catalysts for hydrocarbon functionalization.
• Academic & R&D Laboratories: A staple in research for method development, natural product synthesis, and exploring new boron-mediated transformations.

Basic Information

Item	Detail
Product Name	Pinacolborane
CAS No.	25015-63-8
Molecular Formula	C6H13BO2
Molecular Weight	127.98 g/mol
Synonyms	Pinacol Borane; 4,4,5,5-Tetramethyl-1,3,2-dioxaborolane; Pinacol Diboron; Bis(pinacolato)diboron (Note: This is a common related compound, often searched in conjunction); PinBH; Pinacol Hydroborane; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) (common for derivatives); Pinacol Boronic Ester (general class)
EINECS	Contact for details

Quality Control

Our Pinacolborane is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including NMR (¹H, ¹¹B, ¹³C), GC, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified parameters. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, it is recommended to store at 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Pinacol Content (GC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.