Description

1,3,2-Dioxaborolane, 2-(2'-Chloro[1,1'-Biphenyl]-2-Yl)-4,4,5,5-Tetramethyl- is a high-value, organoboron building block featuring a biphenyl core with a chloro substituent. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl motifs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing functionalized biphenyl structures.
• Material Science Research: Building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for imaging and diagnostic applications.
• Academic & Industrial R&D: Essential for method development and exploratory synthesis in both university and corporate research laboratories.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(2'-Chloro[1,1'-Biphenyl]-2-Yl)-4,4,5,5-Tetramethyl-
CAS No.	2210254-25-2
Molecular Formula	C18H20BClO2
Molecular Weight	314.61 g/mol
Synonyms	2-(2'-Chloro-[1,1'-biphenyl]-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2'-Chloro-2-biphenylboronic acid pinacol ester; 2-(2'-Chlorobiphenyl-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Chloro-2'-pinacolatoborylbiphenyl; (2'-Chloro[1,1'-biphenyl]-2-yl)boronic acid pinacol ester; 2-(2-Chlorophenyl)phenylboronic acid pinacol ester; Chlorinated biphenyl pinacol boronate
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane derivative is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. All products undergo rigorous analytical testing, including NMR, HPLC, and GC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.