Description

7-Azaindole-5-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development programs.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to construct novel 7-azaindole derivatives, a privileged scaffold in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting kinases and other therapeutic proteins.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to the electron-rich nature of the azaindole core.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and inhibitors to study biological pathways and enzyme function.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for drug discovery campaigns.

Basic Information

Product Name	7-Azaindole-5-Boronic Acid Pinacol Ester
CAS No.	16-62-6
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-boronic acid, pinacol ester; 5-(Pinacolatoboryl)-7-azaindole; 7-Azaindol-5-ylboronic acid pinacol ester; 5-Borono-1H-pyrrolo[2,3-b]pyridine pinacol ester; 7-Azaindole-5-boronic acid neopentyl glycol ester (common alternative); Azaindole boronate ester
EINECS	Contact for details

Quality Control

Our 7-Azaindole-5-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.