Description

Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-3-Carboxylate is a high-value, multifunctional boronic ester derivative that serves as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing furan or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require boronic ester coupling steps.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Research: A versatile reagent in academic and industrial R&D for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized for constructing sophisticated ligand frameworks in coordination chemistry and catalysis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance, flavor, and specialty chemical compounds.

Basic Information

Product Name	Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-3-Carboxylate
CAS No.	676501-87-4
Molecular Formula	C12H19BO5
Molecular Weight	254.09 g/mol
Synonyms	Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-furoate; 3-Furancarboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 5-(pinacolatoboran-2-yl)furan-3-carboxylate; 5-(Pinacolatoboryl)furan-3-carboxylic acid methyl ester; Methyl 5-(pinacolboronato)furan-3-carboxylate; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-furoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.