Description

3H-INDOLIUM, 2-[5-[1,3-DIHYDRO-3,3-DIMETHYL-5-SULFO-1-(3-SULFOPROPYL)-2H-INDOL-2-YLIDENE]-1,3-PENTADIENYL]-3,3-DIMETHYL-5-SULFO-1-(3-SULFOPROPYL)-, INNER SALT, TRISODIUM SALT is a high-purity, water-soluble cyanine dye derivative, valued for its strong near-infrared (NIR) absorption and fluorescence properties. This compound is engineered for superior photostability and solubility, making it an essential functional component in advanced material science and diagnostics. It is primarily utilized by researchers and manufacturers in the biotechnology, medical imaging, and specialty chemical sectors for developing sensitive probes and functional materials.

Application

• NIR Fluorescent Probes and Labels: Used as a core chromophore for labeling biomolecules (antibodies, proteins, nucleic acids) in fluorescence microscopy, flow cytometry, and in vivo imaging applications.
• Optical Sensing Materials: Incorporated into polymer matrices, nanoparticles, and thin films for the development of chemical sensors and biosensors targeting specific analytes.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer due to its ability to generate reactive oxygen species upon light activation in therapeutic research.
• Laser Dye and Optical Recording Media: Serves as an active medium in tunable dye lasers and in the formulation of advanced optical data storage materials.
• Functional Dye for Textiles and Plastics: Applied in niche areas for imparting specific optical properties to synthetic fibers and engineering plastics.
• Academic and Industrial R&D: A key intermediate for synthetic chemists developing new cyanine dye derivatives with tailored photophysical characteristics.

Basic Information

Item	Details
Product Name	3H-INDOLIUM, 2-[5-[1,3-DIHYDRO-3,3-DIMETHYL-5-SULFO-1-(3-SULFOPROPYL)-2H-INDOL-2-YLIDENE]-1,3-PENTADIENYL]-3,3-DIMETHYL-5-SULFO-1-(3-SULFOPROPYL)-, INNER SALT, TRISODIUM SALT
CAS No.	190517-63-6
Molecular Formula	C34H41N2Na3O9S3
Molecular Weight	794.87 g/mol
Synonyms	Cyanine5.5 carboxylic acid, trisodium salt; Sulfo-Cy5.5 carboxylic acid; Cy5.5 NHS ester precursor; 2-[5-[1,3-Dihydro-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)indol-2-ylidene]-1,3-pentadienyl]-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)-3H-indolium, inner salt, trisodium salt; NIR-664 dye; IR-1061 analog; Heptamethine cyanine dye, sulfonated; Trisodium 1,1'-(1E,3E)-1-(3-sulfonatopropyl)-5-[(1E,3E)-3-(1,3-dihydro-3,3-dimethyl-5-sulfo-1-(3-sulfonatopropyl)indol-2-ylidene)prop-1-en-1-yl]penta-1,3-dien-1-ylidene]-3,3-dimethylindoline-5-sulfonate
EINECS	Contact for details

Quality Control

Every batch of our cyanine dye is produced under strict quality management and undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the rigorous demands of research and diagnostic applications, ensuring reliable and reproducible results for our customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	Dark green to blue-black solid
Identification (IR)	Conforms to structure
Identification (UV-Vis)	λmax (H2O): 680 - 690 nm
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility (in Water)	Clear, intense blue solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.