Description

3H-Indolium, 1-(5-carboxypentyl)-2-[2-[3-[2-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]ethylidene]-2-chloro-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-, inner salt is a high-purity, functional cyanine dye intermediate with a complex polymethine structure. This compound is valued for its strong near-infrared (NIR) absorption and fluorescence properties, making it a critical building block for advanced optical applications. It is primarily sought by manufacturers in the biotechnology, medical diagnostics, and advanced material science sectors for developing sensitive probes and functional dyes.

Application

• NIR Fluorescent Dye Synthesis: A key precursor for synthesizing heptamethine cyanine dyes used in bioimaging and flow cytometry.
• Bioconjugation Probes: Used to create labeled antibodies, peptides, and nucleic acids for in vitro and in vivo diagnostic assays.
• Optical Sensor Development: Incorporated into polymer matrices or nanoparticles to create sensors for pH, ions, or specific biomolecules.
• Photodynamic Therapy (PDT) Agents: Serves as a starting material for photosensitizers used in cancer treatment research.
• Non-Linear Optical Materials: Utilized in the research and development of materials for photonics and optoelectronics.
• Security Inks and Taggants: Employed in formulating covert markers with specific infrared signatures for anti-counterfeiting.

Basic Information

Product Name	3H-Indolium, 1-(5-carboxypentyl)-2-[2-[3-[2-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]ethylidene]-2-chloro-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-, inner salt
CAS No.	174829-14-2
Molecular Formula	C41H51ClN2O4
Molecular Weight	671.31 g/mol
Synonyms	IR-783 Carboxylic Acid; Heptamethine cyanine dye, carboxylated; 1,1',3,3,3',3'-Hexamethyl-4,4',5,5'-dibenzo-2,2'-indotricarbocyanine-8,8'-dicarboxylic acid (chloro derivative); Cy7.5 carboxylic acid analogue; NIR-783 dye acid; 2-[2-[3-[2-(1,5-Dicarboxypentyl-3,3-dimethylindolin-2-ylidene)ethylidene]-2-chlorocyclohex-1-en-1-yl]vinyl]-1,5-dicarboxypentyl-3,3-dimethyl-3H-indolium
EINECS	Contact for details

Quality Control

Our production of this cyanine dye intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC, Area %)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 1.0%
Absorption λmax	780 - 800 nm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.