Description

(4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione is a complex macrocyclic polyketide derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate spirocyclic and polyhydroxylated structure makes it a valuable precursor or intermediate for developing novel bioactive compounds. This high-purity chemical is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and specialized chemical libraries.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new therapeutic agents, particularly for complex target molecules.
• Organic Synthesis Research: Used as a sophisticated substrate or intermediate in methodological studies and total synthesis projects within academic and industrial laboratories.
• Chemical Biology Probe Development: Its unique structure can be leveraged to create molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, specialized chemicals for niche markets.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in related chemical processes.

Basic Information

Product Name	(4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione
CAS No.	140221-72-3
Molecular Formula	C39H62O9
Molecular Weight	674.9 g/mol
Synonyms	Spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione derivative; Macrocyclic polyketide spiroacetal; CAS 140221-72-3; Polyhydroxylated macrocyclic intermediate; Complex spirocyclic ketone
EINECS	Contact for details

Quality Control

Our (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.