Description

2-[2-[2-CHLORO-3-[2-[1,3-DIHYDRO-3,3-DIMETHYL-5-SULFO-1-(4-SULFOBUTYL)-2H-INDOL-2-YLIDENE]-ETHYLIDENE]-1-CYCLOHEXEN-1-YL]-ETHENYL]3,3-DIMETHYL-5-SULFO-1-(4-SULFOBUTYL)-3H-INDOLIUM HYDROXIDE, INNER SALT, TRIPOTASSIUM SALT is a high-purity, water-soluble cyanine dye derivative, specifically a heptamethine indocyanine green (ICG) analog, valued for its strong near-infrared (NIR) absorption and fluorescence properties. This compound is engineered for applications requiring precise photophysical characteristics, offering excellent stability and functionalization potential. It is a critical material for researchers and manufacturers in the biomedical imaging, optical sensing, and advanced material science sectors.

Application

• Near-Infrared Fluorescence Imaging (NIRF): As a contrast agent for in vivo and in vitro biological imaging, including tumor detection, lymph node mapping, and angiography.
• Optical Sensor Development: Key component in the fabrication of chemical and biological sensors that operate in the NIR window to minimize background interference.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer for targeted cancer treatments due to its light-absorbing properties.
• Laser and Optoelectronic Materials: Used in the formulation of dyes for laser media, optical filters, and non-linear optical materials.
• Bioconjugation and Probes: Serves as a starting material or intermediate for synthesizing labeled antibodies, peptides, and other biomolecular probes.
• Material Science Research: Employed in studies of energy transfer, solar cells, and as a dopant in polymeric matrices for specialized coatings.

Basic Information

Item	Details
Product Name	2-[2-[2-CHLORO-3-[2-[1,3-DIHYDRO-3,3-DIMETHYL-5-SULFO-1-(4-SULFOBUTYL)-2H-INDOL-2-YLIDENE]-ETHYLIDENE]-1-CYCLOHEXEN-1-YL]-ETHENYL]3,3-DIMETHYL-5-SULFO-1-(4-SULFOBUTYL)-3H-INDOLIUM HYDROXIDE, INNER SALT, TRIPOTASSIUM SALT
CAS No.	138081-45-5
Molecular Formula	C47H54ClK3N2O12S4
Molecular Weight	1150.41 g/mol (approx.)
Synonyms	IR-783; IR 783; IR783; Heptamethine cyanine dye, IR-783; 1H-Indolium, 2-[2-[2-chloro-3-[(1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-, hydroxide, inner salt, potassium salt (1:3); Potassium 2-[2-[2-chloro-3-[(1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-1H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-1H-indol-3-ium-3-olate; NIR Dye IR-783; ICG Analog
EINECS	Contact for details

Quality Control

Our production of this advanced cyanine dye adheres to stringent quality protocols to ensure batch-to-batch consistency and performance reliability. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and photophysical properties. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, absorbance/fluorescence maxima, and extinction coefficient is provided with every shipment. We support GMP-grade manufacturing for critical research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-black powder
Identification (HPLC)	Conforms to reference standard
Identification (NIR Absorption)	λmax: 783 ± 5 nm
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition (Sulfated Ash)	≤ 20.0%
Heavy Metals (as Pb)	≤ 20 ppm
Absorbance (Specific)	Reported per COA
Fluorescence Quantum Yield	Reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.