Description

[3aR,6aα,10aα,(-)]-5α-Acetoxy-3,3aα,4,5,6,6a,7,8,9,9a,10,10a-dodecahydro-6α,7β-dihydroxy-7-isopropyl-4β,9aβ-dimethyl-1-methylenedicyclopenta[a,d]cyclooctene-2(1H)-one is a high-purity, complex diterpenoid derivative with a unique fused polycyclic structure. This compound is of significant interest as a key chiral intermediate in advanced organic synthesis, particularly for the development of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams working on complex natural product analogs and specialized chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in steroid and terpenoid-based therapeutic research.
• Advanced Organic Synthesis: Used in complex multi-step syntheses to construct intricate polycyclic frameworks found in natural products.
• Chemical Research & Development: Serves as a reference standard or starting material for exploring new chemical reactions and methodologies in academic and industrial labs.
• Natural Product Analog Development: Enables the modification and derivatization of core diterpenoid structures to study structure-activity relationships (SAR).
• Specialty Fine Chemicals: Employed in the production of high-value, low-volume chemicals for specialized applications in material science or agrochemical research.

Basic Information

Item	Details
Product Name	[3aR,6aα,10aα,(-)]-5α-Acetoxy-3,3aα,4,5,6,6a,7,8,9,9a,10,10a-dodecahydro-6α,7β-dihydroxy-7-isopropyl-4β,9aβ-dimethyl-1-methylenedicyclopenta[a,d]cyclooctene-2(1H)-one
CAS No.	101390-89-0
Molecular Formula	C23H34O5
Molecular Weight	390.52 g/mol
Synonyms	(-)-5α-Acetoxy-3,3aα,4,5,6,6a,7,8,9,9a,10,10a-dodecahydro-6α,7β-dihydroxy-7-isopropyl-4β,9aβ-dimethyl-1-methylenedicyclopenta[a,d]cyclooctene-2(1H)-one; 5α-Acetoxy-7-isopropyl-4β,9aβ-dimethyl-1-methylenedodecahydrocyclopenta[a,d]cyclooctene-2,6,7-triol derivative; Diterpenoid acetate derivative; Complex polycyclic ketone intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles is provided with each shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.