Description

(1aS,7S,7aR,8S)-1a,1b,5,6,6a,7a-Hexahydro-1bα,6β-dihydroxy-6aα-methyl-8-(1-methyl-1-hydroxyethyl)spiro[2α,5α-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepine-7,2'-oxiran]-3(2H)-one is a complex, high-purity synthetic intermediate characterized by its unique polycyclic structure containing multiple oxygenated functional groups. This compound is of significant value for its role as a key chiral building block in advanced organic synthesis, enabling the construction of intricate molecular architectures. It is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those with steroidal or terpenoid-like frameworks.
• Organic Synthesis Research: Used as a versatile chiral synthon in academic and industrial R&D for constructing polycyclic ether and spirocyclic compounds.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development of new catalytic methodologies due to its multiple stereocenters.
• Natural Product Synthesis: A valuable starting material for the total or semi-synthesis of complex natural products with biological activity.
• Process Chemistry Development: Used in scaling up synthetic routes for potential APIs, where its defined stereochemistry is crucial for reproducibility and efficacy.

Basic Information

Item	Details
Product Name	(1aS,7S,7aR,8S)-1a,1b,5,6,6a,7a-Hexahydro-1bα,6β-dihydroxy-6aα-methyl-8-(1-methyl-1-hydroxyethyl)spiro[2α,5α-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepine-7,2'-oxiran]-3(2H)-one
CAS No.	19417-00-6
Molecular Formula	C18H24O7
Molecular Weight	352.38 g/mol
Synonyms	Spiraeoside aglycone derivative; 1b,6-Dihydroxy-6a-methyl-8-(1-hydroxy-1-methylethyl)spiro[2,5-methano-7H-oxireno[3,4]cyclopenta[1,2-d]oxepine-7,2'-oxiran]-3(2H)-one; CAS 19417-00-6; Complex polycyclic oxirane-diol; Advanced chiral spirocyclic intermediate; Hexahydro oxireno-cyclopentoxepinone derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent degradation upon exposure to air. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.