Description

(E)-2-Methyl-2-butenoic acid [(1aR,4E,7S,10aS,10bR)-8-acetoxymethyl-1a,2,3,6,7,9,10a,10b-octahydro-1a,5-dimethyl-9-oxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl] ester is a high-purity, complex organic ester derivative with significant potential in advanced chemical synthesis. This compound is valued for its intricate molecular architecture, which serves as a key chiral building block in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for use in complex multi-step synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new therapeutic agents, particularly for complex natural product analogs.
• Agrochemical Synthesis: Used in the development of advanced, high-specificity pesticides and herbicides requiring sophisticated stereochemical control.
• Fine Chemical Production: Serves as a specialized precursor for synthesizing complex flavors, fragrances, and performance chemicals.
• Academic & Industrial Research: A valuable compound for methodological studies in organic synthesis, catalysis, and stereochemistry.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for complex molecules in pilot plants.

Basic Information

Product Name	(E)-2-Methyl-2-butenoic acid [(1aR,4E,7S,10aS,10bR)-8-acetoxymethyl-1a,2,3,6,7,9,10a,10b-octahydro-1a,5-dimethyl-9-oxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl] ester
CAS No.	11091-28-4
Molecular Formula	C24H30O7
Molecular Weight	430.49 g/mol
Synonyms	Angeloyltigloylglycyrrhetinic Acid; 3-O-Angeloyl-2-O-tigloylglycyrrhetinic Acid; 3-O-(2-Methyl-2-butenoyl)-2-O-((E)-2-methyl-2-butenoyl)glycyrrhetinic Acid; 3β-Angeloyloxy-2α-tigloyloxy-11-oxo-18β-olean-12-en-30-oic Acid; Glycyrrhetinic Acid Angelate Tiglate; 18β-Glycyrrhetinic Acid 3-O-angelate 2-O-tiglate; (3β,20β)-3-[(2Z)-2-Methyl-2-butenoyl]oxy-2-[(2E)-2-methyl-2-butenoyl]oxy-11-oxoolean-12-en-30-oic Acid
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-butenoic acid ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS). We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.