Description

(4R)-4β-(3-Furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-8β-acetic acid methyl ester is a high-purity, complex diterpenoid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical building block for developing novel therapeutic agents and exploring intricate molecular architectures. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and natural product synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new drug candidates, particularly for complex target molecules.
• Medicinal Chemistry Research: Used as a core scaffold or advanced intermediate for structure-activity relationship (SAR) studies and lead optimization.
• Natural Product Synthesis: Acts as a critical intermediate in the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for advanced pharmaceutical ingredients (APIs).
• Academic Research: Provides a valuable compound for teaching and investigating advanced organic synthesis techniques and stereochemistry.

Basic Information

Item	Details
Product Name	(4R)-4β-(3-Furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-8β-acetic acid methyl ester
CAS No.	1915-68-0
Molecular Formula	C27H34O7
Molecular Weight	470.56 g/mol
Synonyms	Methyl 4β-(3-Furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-8β-acetate; 8β-Acetic acid, 4β-(3-furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-, methyl ester; Methyl 4β-(3-furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-8β-acetate; 1915-68-0; Methyl ester of the diterpenoid acid; Furan-containing diterpenoid ester.
EINECS	Contact for details

Quality Control

Our (4R)-4β-(3-Furyl)-1,4,4a,5,6,6aβ,7,8,9,10,11,12-dodecahydro-10α-hydroxy-4aβ,7,9,9-tetramethyl-2,13-dioxo-7β,11β-methano-2H-cycloocta[f][2]benzopyran-8β-acetic acid methyl ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.