Description

(6-Methoxypyrazin-2-Yl)Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic acid derivative used as a key building block in modern organic synthesis. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in constructing heterocyclic scaffolds common in medicinal chemistry.
• Agrochemical Synthesis: Used to develop new active ingredients for crop protection products, leveraging its ability to form carbon-carbon bonds under mild conditions.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile organoboron reagent for palladium-catalyzed coupling with aryl or vinyl halides, enabling the efficient synthesis of biaryl and other conjugated systems.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, where precise molecular architecture is required.
• Chemical Biology & Probe Development: Utilized as a building block for creating molecular probes and labeled compounds used in biochemical assays and diagnostic research.
• Process Chemistry & Scale-Up: Provides a reliable and stable boronate source for optimizing and scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	(6-Methoxypyrazin-2-Yl)Boronic Acid Pinacol Ester
CAS No.	960503-91-7
Molecular Formula	C11H17BN2O3
Molecular Weight	236.08 g/mol
Synonyms	2-(6-Methoxypyrazin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (6-Methoxy-2-pyrazinyl)boronic acid pinacol ester; 6-Methoxypyrazine-2-boronic acid pinacol ester; 2-Methoxypyrazine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxypyrazine; B-(6-Methoxypyrazin-2-yl)boronic acid pinacol ester; 960503-91-7
EINECS	Contact for details

Quality Control

Our (6-Methoxypyrazin-2-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. All products undergo rigorous analytical testing, including NMR, HPLC, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.