Description

3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of novel organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized in the design of molecular sensors and imaging agents for biological and diagnostic applications.

Basic Information

Product Name	3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	960388-56-1
Molecular Formula	C12H16BClO3
Molecular Weight	254.52 g/mol
Synonyms	3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 5-(3-Chlorophenyl)-2,2,5,5-tetramethyl-1,3,2-dioxaborinane; Phenol, 3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Chloro-5-(pinacolatoboryl)phenol; 3-Chloro-5-pinacolboronophenol; 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenol
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC), identity confirmation (by IR and NMR), and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.