Description

1-(5-Fluoro-2-Pyridinyl)-4-Oxo-Cyclohexanecarbonitrile is a high-value, fluorinated heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its unique scaffold enables the creation of novel bioactive molecules. It is primarily sought by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the fluoropyridine moiety.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying enzyme function and biological pathways.
• Advanced Material Synthesis: Acts as a monomer or specialty additive in the development of high-performance polymers and liquid crystals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting custom synthesis and scale-up projects for global clients.

Basic Information

Product Name	1-(5-Fluoro-2-Pyridinyl)-4-Oxo-Cyclohexanecarbonitrile
CAS No.	960371-10-2
Molecular Formula	C₁₂H₉FN₂O
Molecular Weight	216.21 g/mol
Synonyms	4-Oxo-1-(5-fluoro-2-pyridinyl)cyclohexanecarbonitrile; 1-(5-Fluoropyridin-2-yl)-4-oxocyclohexanecarbonitrile; Cyclohexanecarbonitrile, 1-(5-fluoro-2-pyridinyl)-4-oxo-; 960371-10-2; 5-Fluoro-2-(4-oxo-1-cyanocyclohexyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-2-Pyridinyl)-4-Oxo-Cyclohexanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.