Description

8-Cyclopropyl-1,4-Dioxa-Spiro[4.5]Decane-8-Carbonitrile is a specialized spirocyclic nitrile compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique spirocyclic and cyclopropyl architecture makes it a versatile building block for constructing complex molecular frameworks. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring spirocyclic motifs for enhanced metabolic stability.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides, where the cyclopropyl and spirocyclic groups can confer unique biological activity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, three-dimensional structure.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tools to study enzyme function or cellular processes.
• Catalyst Ligand Development: Potential precursor for synthesizing novel chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance or flavor molecules.

Basic Information

Product Name	8-Cyclopropyl-1,4-Dioxa-Spiro[4.5]Decane-8-Carbonitrile
CAS No.	960370-95-0
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	8-Cyclopropyl-1,4-dioxaspiro[4.5]decane-8-carbonitrile; 1,4-Dioxaspiro[4.5]decane-8-carbonitrile, 8-cyclopropyl-; 8-Cyclopropyl-1,4-dioxa-spiro[4.5]decan-8-carbonitrile; Spiro[1,3-dioxolane-2,1'-cyclopentane]-8-carbonitrile, 8-cyclopropyl-; 960370-95-0; 8-Cyclopropyl-1,4-dioxaspiro[4.5]decan-8-carbonitrile
EINECS	Contact for details

Quality Control

Our 8-Cyclopropyl-1,4-Dioxa-Spiro[4.5]Decane-8-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.