Description

6-Methanesulfonamidopyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique sulfonamide and carboxylic acid functionalities enable precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex sulfonamide- and pyridine-containing compounds in academic and industrial R&D.
• Ligand & Catalyst Development: Its functional groups make it suitable for designing specialized ligands for metal catalysis or molecular recognition studies.
• Material Science Precursor: Potential use in synthesizing organic components for advanced materials, such as polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Methanesulfonamidopyridine-3-Carboxylic Acid
CAS No.	960324-86-1
Molecular Formula	C8H8N2O4S
Molecular Weight	228.22 g/mol
Synonyms	6-(Methanesulfonamido)nicotinic Acid; 3-Pyridinecarboxylic acid, 6-[(methylsulfonyl)amino]-; 6-(Methylsulfonylamino)nicotinic Acid; 6-(Methanesulfonylamino)pyridine-3-carboxylic Acid; N-(5-Carboxypyridin-2-yl)methanesulfonamide; 2-(Methylsulfonylamino)-5-pyridinecarboxylic Acid; 960324-86-1; 6-Methanesulfonamido-nicotinic Acid
EINECS	Contact for details

Quality Control

Our 6-Methanesulfonamidopyridine-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We support development and scale-up with customized specifications to meet specific research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.