Description

tert-Butyl 1,8-Diazaspiro[5.5]undecane-1-carboxylate is a high-purity, protected spirocyclic amine building block of significant interest in advanced organic synthesis. Its value lies in its rigid, three-dimensional structure, which is crucial for developing novel compounds with enhanced biological activity and specific physical properties. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures in drug discovery and crop protection programs.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides with new modes of action.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study biological pathways and protein function.
• Peptidomimetics: The spirocyclic amine moiety is valuable for designing conformationally restricted peptide analogs to improve stability and bioavailability.
• Material Science: Potential precursor for specialty polymers and advanced materials requiring specific structural motifs.

Basic Information

Product Name	tert-Butyl 1,8-Diazaspiro[5.5]undecane-1-carboxylate
CAS No.	960294-18-2
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	1,8-Diazaspiro[5.5]undecane-1-carboxylic acid, 1,1-dimethylethyl ester; 1-Boc-1,8-diazaspiro[5.5]undecane; 1-(tert-Butoxycarbonyl)-1,8-diazaspiro[5.5]undecane; tert-Butyl 1,8-diazaspiro[5.5]undecane-1-carboxylate; 1,8-Diazaspiro[5.5]undecane-1-carboxylic acid tert-butyl ester; Boc-1,8-diazaspiro[5.5]undecane; 1-N-Boc-1,8-diazaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our tert-Butyl 1,8-Diazaspiro[5.5]undecane-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.