Description

tert-Butyl 2,6-Diazaspiro[4.5]Decane-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Protease Inhibitor Development: Used in the research and development of inhibitors targeting specific proteases due to its constrained bicyclic amine structure.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 2,6-Diazaspiro[4.5]Decane-6-Carboxylate
CAS No.	960294-16-0
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	6-Boc-2,6-diazaspiro[4.5]decane; 2,6-Diazaspiro[4.5]decane-6-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,6-diazaspiro[4.5]decane-6-carboxylate; 2,6-Diazaspiro[4.5]decane, 6-Boc-protected; Boc-2,6-diazaspiro[4.5]decane; 6-(tert-Butoxycarbonyl)-2,6-diazaspiro[4.5]decane; 1,1-Dimethylethyl 2,6-diazaspiro[4.5]decane-6-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,6-Diazaspiro[4.5]Decane-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.