Description

2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-purity fluorinated pyrimidine derivative, a critical building block in modern organic synthesis. Its value lies in its precise molecular architecture, which serves as a versatile scaffold for constructing complex pharmacologically active molecules. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the fluorophenyl-pyrimidine core.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and liquid crystals.
• Chemical Synthesis: Employed as a versatile building block in cross-coupling reactions and other metal-catalyzed transformations to create diverse chemical libraries.
• Bioconjugation: The ester group can be utilized for further functionalization or as a handle for attaching fluorescent probes or other tags in biochemical applications.

Basic Information

Product Name	2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	960198-50-9
Molecular Formula	C12H9FN2O2
Molecular Weight	232.21 g/mol
Synonyms	Methyl 2-(4-fluorophenyl)pyrimidine-5-carboxylate; 2-(p-Fluorophenyl)-5-pyrimidinecarboxylic acid methyl ester; 5-(Methoxycarbonyl)-2-(4-fluorophenyl)pyrimidine; 2-(4-Fluorophenyl)-5-(methoxycarbonyl)pyrimidine; 960198-50-9; Methyl 2-(4-fluorophenyl)-5-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.