Description

Ethyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-3-Carboxylate is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily used by pharmaceutical, agrochemical, and advanced materials researchers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	Ethyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-3-Carboxylate
CAS No.	960116-27-2
Molecular Formula	C13H21BO4S
Molecular Weight	284.18 g/mol
Synonyms	Ethyl 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylic acid ethyl ester; Ethyl 5-(pinacolatoboryl)thiophene-3-carboxylate; 5-Pinacolatoboryl-thiophene-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.