Description

4,4,5,5-Tetramethyl-2-(4-Phenyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heteroaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional organic molecules. Its defined structure ensures reliable and reproducible reaction outcomes in demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene and biphenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for manufacturing electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Enables the creation of conjugated polymers and organic semiconductors for electronic devices, sensors, and photovoltaic cells.
• Ligand & Catalyst Development: Utilized in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile tool for academic and industrial chemists exploring new carbon-carbon bond-forming methodologies and complex molecule synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-Phenyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane
CAS No.	960116-25-0
Molecular Formula	C16H19BO2S
Molecular Weight	286.20 g/mol
Synonyms	2-(4-Phenylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; Pinacol (4-Phenylthiophen-2-yl)boronate; (4-Phenylthiophen-2-yl)boronic acid pinacol ester; 4-Phenylthiophene-2-boronic acid pinacol ester; 960116-25-0; 4-Phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-thiophene
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(4-Phenyl-Thiophen-2-Yl)-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We are committed to providing materials that meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.