Description

4-Hydroxy-5-Iodonicotinonitrile is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate. This compound is particularly significant for its role in constructing complex molecular architectures, especially in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Hydroxy-5-Iodonicotinonitrile
CAS No.	959972-33-9
Molecular Formula	C6H3IN2O
Molecular Weight	245.01 g/mol
Synonyms	5-Iodo-4-hydroxynicotinonitrile; 4-Hydroxy-5-iodopyridine-3-carbonitrile; 3-Cyano-5-iodopyridin-4-ol; 5-Iodo-4-oxo-1,4-dihydropyridine-3-carbonitrile; Nicotinonitrile, 4-hydroxy-5-iodo-; 959972-33-9
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-5-Iodonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.