Description

Imgatuzumab is a monoclonal antibody designed for targeted therapeutic applications. This product is critical for research and development in advanced oncology and immunology, offering a high-purity reagent for investigative and potential clinical use. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on developing novel cancer treatments. The compound is supplied under stringent quality controls to ensure reliability for sensitive biological applications.

Application

• Oncology Research: Investigation of targeted cancer therapies and tumor biology.
• Immunotherapy Development: Serves as a key reagent in the development of antibody-based immunotherapies.
• Biomarker Studies: Used in assays to identify and validate disease-specific biomarkers.
• Pre-clinical Testing: Essential for in vitro and in vivo efficacy and safety studies.
• Diagnostic Reagent Development: Potential use in the development of companion diagnostics.
• Cell Signaling Research: Tool for studying specific pathways and mechanisms in immune cells.

Basic Information

Product Name	Imgatuzumab
CAS No.	959963-46-3
Molecular Formula	Contact for details
Molecular Weight	Approx. 145-150 kDa (Contact for details)
Synonyms	RO5520985; Anti-CD44 Monoclonal Antibody; GAH; Glycosylated Anti-human CD44 Antibody; Imgatuzumab (RO5520985); Monoclonal Antibody to CD44; RO-5520985; RO5520985
EINECS	Contact for details

Quality Control

Our Imgatuzumab is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, potency, and stability. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications for purity (by SEC-HPLC and CE-SDS), endotoxin levels, and biological activity. We adhere to relevant guidelines for biopharmaceutical materials to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use to prevent degradation.

Specification

Item	Specification
Appearance	Clear to slightly opalescent, colorless to pale yellow solution
Identification (Mass Spec)	Conforms
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Purity (CE-SDS, Reduced)	≥ 90.0% (Heavy + Light Chain)
Protein Concentration	As per COA (Typically 1-10 mg/mL)
Endotoxin	< 1.0 EU/mg
Biological Activity (Binding)	Conforms (e.g., by ELISA or SPR)
Buffer	Specified on COA (e.g., PBS, Histidine buffer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.