Description

Human IL-2 (Interleukin-2) is a critical cytokine protein essential for regulating the immune system's response. This high-purity recombinant protein is vital for research and development in immunology and therapeutic applications. It is primarily utilized by biotechnology firms, pharmaceutical developers, and academic research institutions focused on T-cell biology, cancer immunotherapy, and autoimmune disease studies.

Application

• Immunotherapy Research: A key reagent in the development and study of adoptive cell transfer therapies, such as CAR-T and TIL therapies.
• T-Cell Proliferation & Activation: Used in in vitro assays to stimulate the growth and functional activation of T lymphocytes.
• Cell Culture Supplement: An essential component in media for expanding primary immune cells and certain cell lines.
• Diagnostic Development: Serves as a standard or critical component in immunoassays and diagnostic kits targeting immune function.
• Biopharmaceutical Production: Employed in process development and quality control for biologic drugs targeting the IL-2 pathway.
• Autoimmune & Inflammatory Disease Models: Used to establish and study preclinical models of immune-related disorders.

Basic Information

Product Name	Human IL-2
CAS No.	110942-02-4
Molecular Formula	C690H1114N192O210S10
Molecular Weight	Approx. 15.5 kDa
Synonyms	Interleukin-2; IL-2; T-Cell Growth Factor (TCGF); Aldesleukin (pharmaceutical form); Lymphocyte Mitogenic Factor; Thymocyte Stimulating Factor; Recombinant Human Interleukin-2
EINECS	Contact for details

Quality Control

Our Human IL-2 is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is rigorously tested to confirm identity, purity, potency, and the absence of significant endotoxin contamination. A comprehensive Certificate of Analysis (COA) detailing specifications such as purity by HPLC, biological activity in cell-based assays, and endotoxin levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE & RP-HPLC)	≥ 95%
Biological Activity (Cell Proliferation Assay)	≥ 1 x 107 IU/mg
Endotoxin (LAL Test)	< 1.0 EU/μg
Moisture Content (Karl Fischer)	< 3.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.