Description

4-Aminopyridin-3-Ylboronic Acid Hydrochloride is a high-purity, pharmaceutically relevant boronic acid derivative. This compound serves as a critical building block in modern synthetic organic chemistry, particularly for the construction of complex molecules via cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Used as a versatile boronic acid coupling partner for forming carbon-carbon bonds, crucial for constructing biaryl and heterobiaryl structures.
• Medicinal Chemistry & Drug Discovery: Employed in library synthesis for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Utilized in the development of new herbicides, fungicides, and insecticides.
• Material Science: Potential building block for creating organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Can be used to develop tools for studying biological processes and enzyme inhibition.

Basic Information

Product Name	4-Aminopyridin-3-Ylboronic Acid Hydrochloride
CAS No.	959904-53-1
Molecular Formula	C5H8BClN2O2
Molecular Weight	174.39 g/mol
Synonyms	3-Borono-4-aminopyridine Hydrochloride; 4-Amino-3-pyridineboronic Acid Hydrochloride; (4-Aminopyridin-3-yl)boronic Acid Hydrochloride; 4-Amino-3-pyridinylboronic Acid HCl; 959904-53-1; 3-Pyridineboronic acid, 4-amino-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Aminopyridin-3-Ylboronic Acid Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.