Description

2-Cyclobuten-1-One, 3-Methyl-4-Methylene-2-(Trimethylsilyl)- is a specialized organosilicon building block featuring a highly functionalized cyclobutenone core. This compound is valued for its unique reactivity profile, serving as a versatile precursor in advanced organic synthesis and materials science. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel bioactive molecules and complex natural product analogs.
• Agrochemical Research: Used in the development of new active ingredients with unique modes of action.
• Material Science Precursor: Serves as a building block for advanced polymers and functional organic materials.
• Organic Synthesis Reagent: Utilized in [4+2] cycloaddition reactions and other pericyclic transformations to form complex carbocycles.
• Silicon Chemistry: Exploits the trimethylsilyl group for protective strategies and subsequent functional group manipulations.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new chemical space in discovery chemistry.

Basic Information

Product Name	2-Cyclobuten-1-One, 3-Methyl-4-Methylene-2-(Trimethylsilyl)-
CAS No.	959856-22-5
Molecular Formula	C9H16OSi
Molecular Weight	168.31 g/mol
Synonyms	3-Methyl-4-methylene-2-(trimethylsilyl)cyclobut-2-en-1-one; 2-(Trimethylsilyl)-3-methyl-4-methylen-2-cyclobuten-1-one; 3-Methyl-4-methylene-2-trimethylsilylcyclobutenone; TMS-Cyclobutenone Derivative; Functionalized Cyclobutenone; Silylated Cyclobutenone Building Block
EINECS	Contact for details

Quality Control

Our production of 2-Cyclobuten-1-One, 3-Methyl-4-Methylene-2-(Trimethylsilyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by modern analytical techniques including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.