Description

1,5-Bis[(Trimethylsilyl)Oxy]Naphthalene is a versatile organosilicon-protected naphthalene derivative, primarily serving as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. Its core value lies in providing a robust, silyl-protected phenolic functionality that is stable under a wide range of reaction conditions yet can be selectively deprotected. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where protection of phenolic hydroxyl groups is required during multi-step sequences.
• Agrochemical Synthesis: Serves as a building block for creating advanced active ingredients and herbicides that require naphthalene-based architectures.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed as a protecting group for diols or phenolic compounds in complex natural product and fine chemical synthesis.
• Research & Development: A valuable tool for academic and industrial R&D laboratories exploring new synthetic methodologies and reaction pathways.
• Chemical Derivatization: Used to modify other compounds by introducing the trimethylsilyloxy group for analytical purposes or to alter physical properties.

Basic Information

Product Name	1,5-Bis[(Trimethylsilyl)Oxy]Naphthalene
CAS No.	1032-28-6
Molecular Formula	C16H24O2Si2
Molecular Weight	304.53 g/mol
Synonyms	1,5-Bis(trimethylsiloxy)naphthalene; 1,5-Naphthalenediol, bis(trimethylsilyl) ether; Naphthalene-1,5-diyl bis(oxy)bis(trimethylsilane); 1,5-Di-O-trimethylsilylnaphthalene; 1,5-Bis(trimethylsilyloxy)naphthalene; 1,5-Bis-O-(trimethylsilyl)naphthalene-1,5-diol
EINECS	Contact for details

Quality Control

Our 1,5-Bis[(Trimethylsilyl)Oxy]Naphthalene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.