Description

5-Bromo-2-(Methoxycarbonyl)Pyridine 1-Oxide is a versatile and high-value pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromo substituent and an N-oxide moiety, makes it an essential building block for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry for creating libraries of novel heterocyclic compounds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Ligand Synthesis: Serves as a starting material for the preparation of specialized ligands used in catalysis and coordination chemistry.
• Functional Material Development: Employed in the research and production of advanced organic electronic materials and dyes.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and corporate R&D labs.

Basic Information

Product Name	5-Bromo-2-(Methoxycarbonyl)Pyridine 1-Oxide
CAS No.	959741-32-3
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Methyl 5-Bromopicolinate N-Oxide; 5-Bromo-2-(methoxycarbonyl)pyridine N-Oxide; 5-Bromo-2-(carbonmethoxy)pyridine 1-Oxide; Methyl 5-bromo-2-pyridinecarboxylate 1-oxide; 5-Bromopicolinic Acid Methyl Ester N-Oxide; 2-Methoxycarbonyl-5-bromopyridine N-Oxide
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Methoxycarbonyl)Pyridine 1-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specified requirements. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.