Description

Methyl 2-Chloro-5-Fluoro-6-Methoxynicotinate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its precise molecular architecture, which serves as a key intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used as a building block for developing next-generation herbicides and fungicides with improved efficacy.
• Chemical Research & Development: Serves as a versatile precursor for constructing complex pyridine and nicotinate derivatives in academic and industrial labs.
• Material Science: Potential intermediate for the synthesis of functionalized ligands and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this specific halogenated methoxynicotinate scaffold.

Basic Information

Item	Detail
Product Name	Methyl 2-Chloro-5-Fluoro-6-Methoxynicotinate
CAS No.	959616-64-9
Molecular Formula	C8H7ClFNO3
Molecular Weight	219.60 g/mol
Synonyms	Methyl 2-chloro-5-fluoro-6-methoxypyridine-3-carboxylate; 2-Chloro-5-fluoro-6-methoxy-3-pyridinecarboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 2-chloro-5-fluoro-6-methoxy-, methyl ester; Methyl 2-chloro-5-fluoro-6-methoxynicotinate; 959616-64-9
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Chloro-5-Fluoro-6-Methoxynicotinate adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.