Description

2-(2-Bromophenyl)-1,3,2-Dioxaborinane is a valuable organoboron reagent, specifically a cyclic boronic ester derivative, widely used in modern synthetic chemistry. Its core value lies in its stability and reactivity, serving as a crucial building block for constructing complex molecular architectures through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for forming carbon-carbon bonds, enabling the synthesis of biaryl compounds prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Serves as a protected boronic acid precursor in the multi-step synthesis of complex drug molecules and candidate compounds.
• Agrochemical Research & Development: Used to create novel herbicides, fungicides, and insecticides by introducing the 2-bromophenyl moiety into target structures.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise aryl-aryl linkages are required.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.

Basic Information

Product Name	2-(2-Bromophenyl)-1,3,2-Dioxaborinane
CAS No.	959589-03-8
Molecular Formula	C9H10BBrO2
Molecular Weight	240.89 g/mol
Synonyms	2-(2-Bromophenyl)-1,3,2-dioxaborinane; 2-(2-Bromophenyl)-1,3,2-dioxaborinane; 2-Bromophenylboronic acid 1,3-propanediol ester; 2-Bromophenylboronic acid neopentyl glycol ester; (2-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common alternative structure); 2-Bromophenylboronic acid cyclic ester; B-(2-Bromophenyl)-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 2-(2-Bromophenyl)-1,3,2-Dioxaborinane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and GC for residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.