Description

Methyl 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for carbon-carbon bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyrazole-boronate motifs.
• Material Science: Precursor for organic electronic materials, including OLEDs and organic semiconductors, where precise molecular structure is critical.
• Chemical Research: Enables the synthesis of complex heterocyclic compounds and functionalized molecules in academic and industrial R&D labs.
• Ligand & Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organometallic catalysts.
• Bioconjugation: Potential use in creating bioconjugates and probes for biochemical and diagnostic applications.

Basic Information

Item	Information
Product Name	Methyl 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate
CAS No.	959585-44-5
Molecular Formula	C12H19BN2O4
Molecular Weight	266.10 g/mol
Synonyms	Methyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate; 1H-Pyrazole-1-acetic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetic acid methyl ester; Methyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]acetate; 959585-44-5; Pyrazole boronic ester pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester functionality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.