Description

Dispiro[Cyclohexane-1,3'-[1,2,4]Trioxolane-5',2''-Tricyclo[3.3.1.13,7]Decane]-4-Acetamide, n-(2-Amino-2-Methylpropyl)-, cis-, (2Z)-2-Butenedioate (1:1) is a high-purity, complex organic compound featuring a unique dispiro and adamantane-derived tricyclic framework. This compound is valued for its sophisticated molecular architecture, which makes it a critical intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Advanced Organic Synthesis: Used as a precursor for constructing complex molecular scaffolds in medicinal chemistry and chemical biology research.
• Agrochemical Research: Acts as an intermediate in the development of new-generation pesticides or herbicides with specific modes of action.
• Material Science Precursor: Potential use in synthesizing specialty polymers or organic electronic materials due to its rigid, three-dimensional structure.
• Chemical Biology Probe Development: Utilized in creating labeled compounds or probes for studying biological pathways and target engagement.
• Catalyst Ligand Synthesis: The structural motifs may be modified to create novel ligands for asymmetric catalysis.

Basic Information

Product Name	Dispiro[Cyclohexane-1,3'-[1,2,4]Trioxolane-5',2''-Tricyclo[3.3.1.13,7]Decane]-4-Acetamide, n-(2-Amino-2-Methylpropyl)-, cis-, (2Z)-2-Butenedioate (1:1)
CAS No.	959520-73-1
Molecular Formula	C₂₄H₃₈N₂O₆
Molecular Weight	450.57 g/mol
Synonyms	cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetamide, N-(2-amino-2-methylpropyl)-, (2Z)-2-butenedioate (1:1); (2Z)-2-Butenedioic acid compound with N-[2-(aminomethyl)-2-methylpropyl]-4-[(1S,3S,5S,7S)-3-[(3S,5R)-3,5-dimethyl-1,2,4-trioxolan-3-yl]tricyclo[3.3.1.13,7]dec-1-yl]acetamide (1:1); OZ609 fumarate salt; Artemisinin-derived trioxolane adamantane acetamide fumarate; Artemisone intermediate analog; Spiro-1,2,4-trioxolane adamantane derivative.
EINECS	Contact for details

Quality Control

Our Dispiro[Cyclohexane-1,3'-[1,2,4]Trioxolane-5',2''-Tricyclo[3.3.1.13,7]Decane]-4-Acetamide, n-(2-Amino-2-Methylpropyl)-, cis-, (2Z)-2-Butenedioate (1:1) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, chiral purity, and impurity profiles. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F). The product is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.