Description

Chloroquine Sulfate CAS NO 132-73-0 is the sulfate salt form of chloroquine, a well-established 4-aminoquinoline compound. This active pharmaceutical ingredient (API) is critical for its potent antimalarial and immunomodulatory properties. It is primarily required by the pharmaceutical industry for the formulation of antimalarial drugs and is also utilized in research for investigating autoimmune disorders and certain viral infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in antimalarial tablet and injectable formulations.
• Research Chemical: Used in in vitro and in vivo studies for its effects on autophagy, immune response modulation, and viral replication inhibition.
• Rheumatology: Investigational applications in the management of autoimmune conditions such as rheumatoid arthritis and lupus erythematosus.
• Veterinary Medicine: Employed in the treatment of avian malaria and certain protozoal infections in animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.

Basic Information

Product Name	Chloroquine Sulfate
CAS No.	132-73-0
Molecular Formula	C₁₈H₂₆ClN₃·H₂SO₄
Molecular Weight	436.0 g/mol (as free base: 319.9)
Synonyms	Chloroquine Sulphate; 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline Sulfate; Arelan; Aralen Phosphate (related salt); Resochin; Nivaquine; SN 7618; Gontscho.
EINECS	205-063-8

Quality Control

Our Chloroquine Sulfate is manufactured under strict quality management systems. It is tested to meet relevant pharmacopeial standards (such as USP/EP monographs where applicable) for identity, purity, and potency. Comprehensive testing includes assay, related substances, residual solvents, and microbiological examination. A Certificate of Analysis (COA) is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets requirements for pharmaceutical substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.