Description

Chloroquinine Phosphate CAS NO 1446-17-9 is a pharmaceutical intermediate and active ingredient of significant importance in medicinal chemistry. It serves as a key precursor in the synthesis of antimalarial and antiviral agents, where consistent quality and purity are critical for efficacy and safety. This compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors developing therapeutic formulations.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of antimalarial drugs like chloroquine and hydroxychloroquine.
• Antiviral Research: Investigated as a precursor or reference standard in the development of broad-spectrum antiviral therapies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a direct starting material in GMP-compliant production processes for finished dosage forms.
• Biochemical Research: Used in laboratory studies to understand mechanisms of action against parasitic and viral infections.
• Reference Standard: Employed in analytical laboratories for quality control, method development, and calibration in pharmaceutical analysis.
• Fine Chemical Synthesis: Utilized in organic synthesis to create novel quinoline-based derivatives for pharmacological screening.

Basic Information

Product Name	Chloroquinine Phosphate
CAS No.	1446-17-9
Molecular Formula	C₁₈H₂₆ClN₃·2H₃PO₄
Molecular Weight	515.86 g/mol
Synonyms	Chloroquine Phosphate Impurity; 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline Phosphate; N4-(7-Chloro-4-quinolyl)-N1,N1-diethyl-1,4-pentanediamine Phosphate; Chloroquine Diphosphate; SN-7618; Resochin; Aralen Phosphate; Gamanil
EINECS	215-910-9

Quality Control

Our Chloroquinine Phosphate is produced and tested under a strict quality management system. We ensure compliance with relevant pharmaceutical intermediate standards, and our quality control includes rigorous testing for identity, purity, and impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each batch to guarantee traceability and meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.