Description

Quinine Hydrochloride is the hydrochloride salt form of the naturally occurring alkaloid quinine, a critical compound with a long history of therapeutic use. Its primary commercial value lies in its potent antimalarial activity and its role as a key analytical standard and pharmaceutical intermediate. This high-purity product is essential for manufacturers and research institutions in the pharmaceutical, analytical chemistry, and fine chemical sectors who require a reliable and well-characterized active ingredient.

Application

• Pharmaceutical Active Ingredient (API): Serves as a key starting material or intermediate in the synthesis of antimalarial drugs and other therapeutic agents.
• Analytical Reference Standard: Used in High-Performance Liquid Chromatography (HPLC), spectroscopy, and other analytical methods for quality control, method validation, and research.
• Biochemical Research: Employed in pharmacological and physiological studies to investigate its effects on muscle function, cardiac rhythm, and parasitic diseases.
• Bittering Agent: Historically used as a flavoring agent in tonic water and other beverages; relevant for food and beverage ingredient suppliers.
• Chemical Synthesis: Acts as a chiral building block or precursor in the synthesis of more complex organic molecules and derivatives.

Basic Information

Product Name	Quinine Hydrochloride
CAS No.	130-89-2
Molecular Formula	C20H24N2O2·HCl
Molecular Weight	360.88 g/mol
Synonyms	Quinine HCl; Quinine Monohydrochloride; (8S,9R)-6'-Methoxycinchonan-9-ol hydrochloride; Cinchonan-9-ol, 6'-methoxy-, hydrochloride, (8α,9R)-; 130-89-2; Quinine chloride
EINECS	204-003-9

Quality Control

Our Quinine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Optical Rotation	-245° to -258° (c = 2 in 0.1M HCl)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.