Description

Cyclopropanemethanol, -α--Methyl-2-Methylene-1-(Trimethylsilyl)- is a specialized organosilicon compound featuring a reactive methylene group and a cyclopropane moiety. This unique structure makes it a valuable high-purity synthetic intermediate for constructing complex molecular architectures in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring cyclopropane or silicon-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Organometallic Chemistry: Serves as a precursor or ligand in catalytic systems and the preparation of organosilicon reagents.
• Material Science Research: Employed in the development of specialty polymers, coatings, or silicon-based advanced materials.
• Cross-Coupling Reactions: The trimethylsilyl and methylene groups make it a suitable substrate for various palladium-catalyzed and other metal-mediated coupling reactions.
• Academic & Industrial R&D: A versatile reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Item	Details
Product Name	Cyclopropanemethanol, -α--Methyl-2-Methylene-1-(Trimethylsilyl)-
CAS No.	959292-61-6
Molecular Formula	C9H18OSi
Molecular Weight	170.33 g/mol
Synonyms	1-(Trimethylsilyl)-2-methylene-1-(1-methylcyclopropyl)methanol; (1-Methylcyclopropyl)(trimethylsilyl)methylenemethanol; α-Methyl-2-methylene-1-(trimethylsilyl)cyclopropanemethanol; 2-Methylene-1-(trimethylsilyl)-1-(1-methylcyclopropyl)methanol
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard research-grade material is characterized by multiple analytical techniques including NMR, GC, and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.