Description

3-Bromo-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of a bromine substituent for cross-coupling reactions and a carboxylic acid group for amide bond formation, all on a pyridine scaffold modified with a trifluoromethyl group. This unique structure makes it a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves metabolic stability and bioavailability.
• Ligand & Catalyst Development: The pyridine nitrogen and carboxylic acid functionality make it suitable for constructing complex chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure and halogenated sites.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	959245-76-2
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-bromo-5-(trifluoromethyl)-; 3-Bromo-5-(trifluoromethyl)picolinic acid; 3-Bromo-5-trifluoromethylpyridine-2-carboxylic acid; 959245-76-2; 3-Bromo-5-trifluoromethyl-2-pyridinecarboxylic acid; 3-Bromo-5-(trifluoromethyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are available upon request, providing full traceability and supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.