Description

2-Furancarboxylic Acid, Tetrahydro-, Trimethylsilyl Ester is a specialized organosilicon derivative of tetrahydrofuran-2-carboxylic acid, serving as a valuable protected intermediate and derivatization agent in advanced organic synthesis. Its primary value lies in enabling precise synthetic pathways where moisture-sensitive functional groups require temporary protection, ensuring high-yield reactions and product purity. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), where the trimethylsilyl group acts as a protecting group for carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators requiring specific stereochemistry and functional group manipulation.
• Fine Chemical Manufacturing: Employed as a versatile reagent for the preparation of specialty chemicals, flavors, fragrances, and advanced material precursors.
• Derivatization Agent for Analysis: Utilized in gas chromatography (GC) and mass spectrometry (MS) to derivative polar compounds like carboxylic acids, improving their volatility and detection characteristics.
• Academic & Industrial R&D: Serves as a critical tool in methodological development and exploratory synthesis within university laboratories and corporate research centers.
• Polymer & Material Science: Potential monomer or modifying agent in the development of specialty polymers with tailored thermal or chemical properties.

Basic Information

Product Name	2-Furancarboxylic Acid, Tetrahydro-, Trimethylsilyl Ester
CAS No.	959236-01-2
Molecular Formula	C9H18O3Si
Molecular Weight	202.32 g/mol
Synonyms	Tetrahydro-2-furoic Acid Trimethylsilyl Ester; Trimethylsilyl Tetrahydro-2-furoate; Tetrahydrofuran-2-carboxylic Acid Trimethylsilyl Ester; 2-(Trimethylsilyloxycarbonyl)tetrahydrofuran; (Tetrahydro-2-furanyl)carboxylic Acid Trimethylsilyl Ester; O-Trimethylsilyl Tetrahydrofuroate; Silylating Agent for Tetrahydrofuroic Acid
EINECS	Contact for details

Quality Control

Our production of 2-Furancarboxylic Acid, Tetrahydro-, Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality management system and can support development projects requiring specific analytical data or custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.