Description

Thiophene, 2-Methyl-5-[[(Trimethylsilyl)Oxy]Methyl]- is a high-value organosilicon-functionalized thiophene derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound is engineered to provide a protected hydroxymethyl group, enabling precise and efficient construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and anti-infective agents.
• Functional Polymer Precursor: Used in the development of conjugated polymers and organic semiconductors for applications in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in academic and industrial R&D for constructing complex heterocyclic cores and studying structure-property relationships.
• Agrochemical Intermediate: Potential use in the synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probe Development: Useful for creating tagged molecules to study biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	Thiophene, 2-Methyl-5-[[(Trimethylsilyl)Oxy]Methyl]-
CAS No.	959087-62-8
Molecular Formula	C10H18OSSi
Molecular Weight	214.40 g/mol
Synonyms	2-Methyl-5-((trimethylsilyloxy)methyl)thiophene; 5-((Trimethylsilyloxy)methyl)-2-methylthiophene; (2-Methylthiophen-5-yl)methoxytrimethylsilane; TMS-protected 5-(hydroxymethyl)-2-methylthiophene; 2-Methyl-5-(trimethylsilyloxymethyl)thiophene; 2-Methyl-5-(TMS-oxymethyl)thiophene; 959087-62-8
EINECS	Contact for details

Quality Control

Our production of Thiophene, 2-Methyl-5-[[(Trimethylsilyl)Oxy]Methyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.